Association between body composition, survival, and toxicity in advanced esophagogastric cancer patients receiving palliative chemotherapy.
Willemieke P M DijksterhuisMaarten J PruijtStephanie O van der WoudeRemy KlaassenSophie A KurkMartijn G H van OijenHanneke W M van LaarhovenPublished in: Journal of cachexia, sarcopenia and muscle (2019)
Sarcopenia was not associated with survival or treatment-related toxicity in advanced esophagogastric cancer patients treated with CapOx. Pre-treatment sarcopenic obesity was independently associated with the occurrence of grade 2-4 neurotoxicity and skeletal muscle density with grade 3-4 toxicity.
Keyphrases
- body composition
- skeletal muscle
- papillary thyroid
- oxidative stress
- insulin resistance
- type diabetes
- squamous cell
- resistance training
- squamous cell carcinoma
- palliative care
- bone mineral density
- combination therapy
- childhood cancer
- physical activity
- free survival
- radiation therapy
- body mass index
- adipose tissue
- replacement therapy
- weight gain
- high fat diet induced
- oxide nanoparticles
- community dwelling