Glycyrrhetinic acid blocks SARS-CoV-2 infection by activating the cGAS-STING signalling pathway.

Hui QiQin-Hai MaWei FengSi-Mian ChenCai-Sheng WuYanan WangTong-Xing WangYun-Long HouZhen-Hua Jia

Published in: British journal of pharmacology (2024)

Activation of the cGAS-STING pathway through the GA-STING-IRF3 axis is essential for the antiviral activity of GA in mice, providing new insights into the potential translation of GA for treating SARS-CoV-2 in patients.

Keyphrases

pet ct
sars cov
end stage renal disease
ejection fraction
newly diagnosed
respiratory syndrome coronavirus
chronic kidney disease
prognostic factors
peritoneal dialysis
metabolic syndrome
risk assessment
adipose tissue