Small GTPase RHOE/RND3, a new critical regulator of NF-κB signalling in glioblastoma multiforme?

Qian SunHuimin DongYuntao LiFan'en YuanYang XuShanping MaoXiaoxing XiongQian-Xue Chen Bao-Hui Liu

Published in: Cell proliferation (2019)

RND3 binds p65 protein and promotes its ubiquitination, resulting in reduced p65 protein expression and inhibition of NF-κB signalling to induce GBM cell apoptosis.

Keyphrases

signaling pathway
lps induced
pi k akt
nuclear factor
oxidative stress
transcription factor
inflammatory response
protein protein
toll like receptor
binding protein
amino acid