High-sensitivity detection of Mycobacterium tuberculosis DNA in tongue swab samples.
Alaina M OlsonRachel C WoodKris M WeigelAlexander J YanKatherine A LochnerRane B DragovichAngelique K LuabeyaPaul YagerMark HatherillGerard A CangelosiPublished in: medRxiv : the preprint server for health sciences (2024)
Improved testing for tuberculosis (TB) is needed. Using a more accessible sample type than sputum may enable the detection of more cases, but it is critical that alternative samples be tested appropriately. Here, we describe two new, highly accurate methods for testing tongue swabs for TB DNA.