Analysis and visualization of the course and burden over time of adverse drug reactions (ADRs) attributed to TNFα-inhibitors in patients with inflammatory rheumatic diseases (IRDs).

Merel de BoerHelen R GosseltJurriaan JansenMartijn Bastiaan Adriaan van DoornFrank HoentjenMichael T NurmohamedPhyllis I SpulsSander W TasHarald E Vonkeman Naomi T Jessurun

Published in: Expert opinion on drug safety (2022)

Skin reactions attributed to TNFα-inhibitors by IRD-patients are stable with a slightly decreasing burden over time. Infections have highest burden at start but resolved mostly. Injection site reactions have a low and stable burden. Sankey diagrams and polar plots are suitable to visualize this.

Keyphrases

adverse drug
end stage renal disease
rheumatoid arthritis
risk factors
chronic kidney disease
newly diagnosed
emergency department
peritoneal dialysis
ultrasound guided
patient reported