Role of Helicobacter pylori infection in cancer-associated fibroblast-induced epithelial-mesenchymal transition in vitro.

Gracjana Krzysiek-MaczkaAneta TargoszUrszula SzczyrkMalgorzata StrzałkaZbigniew SliwowskiTomasz BrzozowskiJarosław CzyzAgata Ptak-Belowska

Published in: Helicobacter (2018)

Helicobacter pylori (cagA+vacA+) strain induces differentiation of normal fibroblasts into CAFs, likely to initiate the EMT process in RGM-1 epithelial cell line.

Keyphrases

helicobacter pylori
helicobacter pylori infection
epithelial mesenchymal transition
transforming growth factor
high glucose
signaling pathway
drug induced
extracellular matrix
endothelial cells
wound healing