1-year weight change after diabetes diagnosis and long-term incidence and sustainability of remission of type 2 diabetes in real-world settings in Hong Kong: An observational cohort study.
Hongjiang WuAimin YangEric S H LauXinge ZhangBaoqi FanRonald Ching-Wan MaAlice Pik-Shan KongElaine Y K ChowWing-Yee SoJuliana Chung Ngor ChanAndrea On Yan LukPublished in: PLoS medicine (2024)
In this study, greater weight loss within the first year of diabetes diagnosis was associated with an increased likelihood of achieving diabetes remission and a decreased risk of returning to hyperglycaemia among those who had achieved diabetes remission. However, both the incidence of diabetes remission and the probability of its long-term sustainability were low with conventional management in real-world settings, in an era when the importance of weight loss was not fully appreciated. Our study provides evidence for policymakers to design and implement early weight management interventions and diabetes remission initiatives.