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Impact of severe diabetic kidney disease on the clinical outcome of autologous cell therapy in people with diabetes and critical limb ischaemia.

Michal DubskýA JirkovskáR BemA NěmcováV FejfarováJ HazdrováK SutorisJ ChlupáčJ SkibováE B Jude
Published in: Diabetic medicine : a journal of the British Diabetic Association (2019)
The present study shows that autologous cell therapy in people with severe diabetic kidney disease significantly improved critical limb ischaemia and lengthened amputation-free survival in comparison with conservative treatment; however, the treatment did not influence overall survival.
Keyphrases
  • cell therapy
  • free survival
  • stem cells
  • mesenchymal stem cells
  • type diabetes
  • cardiovascular disease
  • bone marrow
  • early onset
  • wound healing
  • skeletal muscle
  • weight loss