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Downregulation of Heat Shock Protein 72 Contributes to Fibrostenosis in Crohn's Disease.

Seung Won KimJae-Young LeeHan Cheol LeeJae Bum AhnJi Hyung KimI Seul ParkJae Hee CheonDuk Hwan Kim
Published in: Gut and liver (2023)
HSP72 is an important mediator that regulates myofibroblasts and epithelial-mesenchymal transition in fibrosis of CD, suggesting that HSP72 can serve as a target for antifibrotic therapy.
Keyphrases
  • heat shock protein
  • epithelial mesenchymal transition
  • signaling pathway
  • heat shock
  • transforming growth factor
  • cell proliferation
  • pulmonary fibrosis
  • liver fibrosis
  • bone marrow