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Ado-trastuzumab emtansine: Avoiding side-effects of traditional HER2 positive breast cancer treatment.

Alla TurshudzhyanJames Vredenburgh
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2021)
Some recent studies discussed in this case showed that first-line therapies don't have significant progression free survival advantage when compared to the second-line therapy that our patient received. Ado-trastuzumab emtansine is a potent cytotoxic drug connected via a stable linker to the anti-HER2 antibody, trastuzumab. More studies need to be done to further investigate positive result presented in this case and whether this could be considered an alternative to current first-line therapy.
Keyphrases
  • metastatic breast cancer
  • free survival
  • epidermal growth factor receptor
  • positive breast cancer
  • case control
  • case report
  • tyrosine kinase
  • mesenchymal stem cells
  • bone marrow
  • cell therapy
  • drug induced