Single versus Multiple Dose Ivermectin Regimen in Onchocerciasis-Infected Persons with Epilepsy Treated with Phenobarbital: A Randomized Clinical Trial in the Democratic Republic of Congo.
Michel MandroJoseph Nelson Fodjo SieweAlfred DusabimanaDeby MukendiSteven HaesendonckxRichard LokondaSwabra NakatoFrancoise NyisiGermain AbhafuleD Wonya'rossiAn HotterbeekxSteven AbramsRobert ColebundersPublished in: Pathogens (Basel, Switzerland) (2020)
Increasing the number of ivermectin treatments was found to suppress both microfilarial density and seizure frequency in OIPWE, suggesting that O. volvulus infection plays an etiological role in causing seizures.