TGF-β Inhibitors in Metastatic Pancreatic Ductal Adenocarcinoma.

Marcus A AlvarezJúlia Pedó FreitasS Mazher HussainEvan S Glazer

Published in: Journal of gastrointestinal cancer (2019)

This review clarifies the recent literature investigating the role of anti-TGF-β-based therapy in PDAC and areas ripe for targeted investigations and therapies.

Keyphrases

transforming growth factor
squamous cell carcinoma
systematic review
small cell lung cancer
cancer therapy
epithelial mesenchymal transition
stem cells
signaling pathway
smoking cessation