Systemic administration of quality- and quantity-controlled PBMNCs reduces bisphosphonate-related osteonecrosis of jaw-like lesions in mice.

Shinichiro KuroshimaKazunori NakajimaMuneteru SasakiTakashi IYoshinori SumitaTakayuki AsaharaIzumi AsahinaTakashi Sawase

Published in: Stem cell research & therapy (2019)

Our findings suggest that transplantation of a small amount of QQ-controlled PBMNCs may become novel therapeutic or prevention strategies for BRONJ without any adverse side effects.

Keyphrases

emergency department
cell therapy
stem cells
adipose tissue
mesenchymal stem cells
metabolic syndrome
skeletal muscle
insulin resistance
electronic health record