A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients.

Mohammad Sadegh Soltani-ZangbarForough ParhizkarElham GhaediAli TarbiatRoza MotavalliAmin AlizadeganLeili Aghebati-MalekiDavoud RostamzadehYousef YousefzadehGolamreza JadideslamSima Shahmohammadi FaridLeila RoshangarAta MahmoodpoorJavad Ahmadian HerisAbolfazl MiahipourMehdi Yousefi

Published in: Cell communication and signaling : CCS (2022)

Our results indicate a positive association of the existence of anti-IFN-α autoantibodies and immune cells dysregulation with the severity of illness in COVID-19 patients. However, comprehensive studies are necessary to find out more about this context. Video abstract.

Keyphrases

sars cov
signaling pathway
dendritic cells
systemic lupus erythematosus
immune response
pi k akt
case control