Interruption of perivascular sympathetic nerves of cerebral arteries offers neuroprotection against ischemia.

Reggie Hui-Chao LeeAlexandre Couto E SilvaFrancesca M LernerCarl S WilkinsStephen E ValidoDaniel D KleinCeleste Y WuJake T NeumannDavid Della-MorteStephen H KoslowAlireza MinagarHung Wen Lin

Published in: American journal of physiology. Heart and circulatory physiology (2016)

Interruption of the perivascular sympathetic nerves can alleviate CA-induced hypoperfusion and neuronal cell death in the CA1 region of the hippocampus to enhance functional learning and memory.

Keyphrases

cerebral ischemia
cell death
subarachnoid hemorrhage
brain injury
cognitive impairment
blood brain barrier
high glucose
diabetic rats
protein kinase
drug induced
cell cycle arrest
endothelial cells
oxidative stress
stress induced