A new generation of recombinant polypeptides combines multiple protein domains for effective antimicrobial activity.
Ramon Roca-PinillaAdrià López-CanoCristina SaubiElena Garcia-FruitósAnna ArísPublished in: Microbial cell factories (2020)
Our findings demonstrated that multidomain antimicrobial proteins forming nanoclusters can be efficiently produced in recombinant bacteria, being a novel and valuable strategy to create a versatile, highly stable and easily editable multidomain constructs with a broad-spectrum antimicrobial activity in both soluble and nanostructured format.