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Genomics of human pulmonary tuberculosis: from genes to pathways.

Catherine M SteinLindsay SausvilleChristian WejseRafal S SobotaNicola M ZetolaPhilip C HillW Henry BoomWilliam K ScottGiorgio SirugoScott M Williams
Published in: Current genetic medicine reports (2017)
Several pathways were significantly enriched using pathway analyses that may help to explain population patterns of TB risk. In conclusion, we advocate for novel approaches to the study of host genetic analysis of TB that extend traditional association approaches.
Keyphrases
  • pulmonary tuberculosis
  • mycobacterium tuberculosis
  • genome wide
  • endothelial cells
  • single cell
  • induced pluripotent stem cells
  • dna methylation
  • copy number
  • genome wide identification