Red blood cell distribution width as an easily measurable biomarker of persistent inflammation and T cell dysregulation in antiretrovirally treated HIV-infected adults.
Zao ZhangGlen M ChewCecilia M ShikumaLouie Mar A GangcuangcoScott A SouzaBruce ShiramizuBeau K NakamotoTing GongSanthosh R MannemBrooks I MitchellKalpana J KallianpurLishomwa C NdhlovuDominic C ChowPublished in: HIV clinical trials (2018)
Our study revealed correlations between RDW with systemic inflammatory biomarkers and CD8+ T-cell populations related to immune activation and exhaustion in HIV-infected individuals on ART. Further studies are warranted to determine the utility of RDW as a marker of immune dysregulation in HIV.