Pharmacodynamic Material Basis and Potential Mechanism Study of Spatholobi Caulis in Reversing Osteoporosis.

Jianpeng XiaoWei ShangZhiming ZhaoJun Jiang Jianping Chen Hui Cai Jinjin HeZhihui CaiZihan Zhao

Published in: Evidence-based complementary and alternative medicine : eCAM (2023)

SC had the hierarchical network characteristics of "multicomponents/multitargets/multifunctions/multipathways" in reversing OP, but AGE-RAGE signaling pathway may be the main regulatory mechanism.

Keyphrases

signaling pathway
postmenopausal women
pi k akt
transcription factor
epithelial mesenchymal transition
bone mineral density
oxidative stress
induced apoptosis