Should We Consider Deep Brain Stimulation Discontinuation in Late-Stage Parkinson's Disease?

Margherita FabbriMaurizio ZibettiMario Giorgio RizzoneGiulia GianniniLinda BorelliniAlessandro StefaniFrancesco BoveAndrea BrunoGiovanna Calandra-BuonauraNicola ModugnoCarla PianoAntonella PeppeGianluca Ardolino Alberto Romagnolo Carlo Alberto ArtusiPaola BerchiallaElisa MontanaroPietro CortelliLuigi Michele RomitoRoberto EleopraBrigida MinafraClaudio PacchettiTommaso TufoFilippo CogiamanianLeonardo Lopiano

Published in: Movement disorders : official journal of the Movement Disorder Society (2020)

The vast majority of late-stage PD patients (92%) show a meaningful response to STN-DBS. Effects of stimulation may take days to disappear after its discontinuation. We present a safe and effective decisional algorithm that could guide physicians and caregivers in making challenging therapeutic decisions in late-stage PD. © 2020 International Parkinson and Movement Disorder Society.

Keyphrases

deep brain stimulation
parkinson disease
end stage renal disease
obsessive compulsive disorder
chronic kidney disease
newly diagnosed
ejection fraction
primary care
machine learning
palliative care
prognostic factors