Worldwide distribution of genetic factors related to severity of COVID-19 infection.

María Esther EstebanDébora PinoAlicia Romero-LorcaApolonia NovilloMaría GaibarJosé A RianchoAugusto Rojas-MartínezCarlos FloresPablo LapunzinaÁngel Carracedonull nullGeorgios AthanasiadisAna Fernández-Santander

Published in: Annals of human biology (2024)

Considering the caveats of PRS transferability across ethnicities, our analysis showed that American populations present the highest genetic risk score, hence potentially higher propensity, for COVID-19 severity. Independent validation is warranted with additional summary statistics and phenotype data.

Keyphrases

coronavirus disease
genome wide
sars cov
copy number
big data
dna methylation
genetic diversity
respiratory syndrome coronavirus