Retinal microvasculature dysfunction is associated with Alzheimer's disease and mild cognitive impairment.
Jacqueline ChuaQinglan HuMengyuan KeBingyao TanJimmy HongXinwen YaoSaima HilalNarayanaswamy VenketasubramanianGerhard GarhöferCarol Y CheungTien Yin WongChristopher Li-Hsian ChenLeopold SchmettererPublished in: Alzheimer's research & therapy (2020)
Eyes of patients with AD have significantly reduced macular VD in both plexuses whereas MCI participants only showed reduction in the superficial plexus. Changes in the retinal microvasculature and capillary network may offer a valuable insight on the brain in AD.