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Channel Behavior and Voltage Gating of a Cx43 Mutant Simulating Preconditioning.

Jose F Ek-VitorinDiego Silva-MendozaTasha K PontifexJanis M Burt
Published in: Bioelectricity (2023)
Ischemic preconditioning and the ensuing phosphorylation of Cx43 by PKC may render junctional channels insensitive to transjunctional voltages, allowing the preservation of intercellular communication in ischemic conditions.
Keyphrases
  • ischemia reperfusion injury
  • cerebral ischemia
  • subarachnoid hemorrhage
  • oxidative stress
  • blood brain barrier
  • brain injury
  • protein kinase