Increased hepatotoxicity among HIV-infected adults co-infected with Schistosoma mansoni in Tanzania: A cross-sectional study.

Amon I MartiSoledad ColombePeter J MasikiniSamuel E KalluvyaLuke R SmartBahati M WajangaHyasinta JakaRobert N PeckJennifer A Downs

Published in: PLoS neglected tropical diseases (2017)

Our work demonstrates a strong association between S. mansoni infection and hepatotoxicity among HIV-infected patients on antiretroviral therapy. Our study highlights the importance of schistosome screening and treatment for patients starting antiretroviral therapy in schistosome-endemic settings. Additional studies to determine the effects of schistosome-HIV co-infections are warranted.

Keyphrases

antiretroviral therapy
hiv infected
hiv infected patients
hiv positive
human immunodeficiency virus
hiv aids
end stage renal disease
ejection fraction
drug induced
physical activity
chronic kidney disease
risk factors
men who have sex with men