A review of therapy-related myelodysplastic syndromes and acute myeloid leukaemia (t-MDS/AML) in Irish patients: a single centre experience.

Su W MaungCathie BurkeJennifer HaydeJanice WalsheRay S McDermottRonan DesmondJohnny McHughHelen Enright

Published in: Hematology (Amsterdam, Netherlands) (2017)

t-MDS/AML patients showed unique characteristics which influenced their treatment and outcomes. IPSS-R may be useful in risk-adapted treatment approaches and can predict outcomes. Survival remains poor but improved outcomes were seen with allogeneic transplantation. Azacitidine may be effective in patients unfit for intensive therapies.

Keyphrases

end stage renal disease
ejection fraction
acute myeloid leukemia
newly diagnosed
bone marrow
primary care
intensive care unit
hepatitis b virus
liver failure
cell therapy
mechanical ventilation
acute respiratory distress syndrome
general practice
aortic dissection
breast cancer risk