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Aminoglycoside induced ototoxicity risk in the cystic fibrosis population: The utility of large-scale screening.

Jaime L LopesNoemi Vidal-FolchPatrick LundquistLisa A SchimmentiNadir DemirelVicki DeanJanelle OlsonTom AuthMalinda ButzKatelyn ReedMark E WylamJessica BalcomNicole J BoczekLinda Hasadsri
Published in: Pediatric pulmonology (2022)
Our findings demonstrate the utility of pretreatment screening in the cystic fibrosis population for AIHL risk using ddPCR, a scalable and robust testing methodology at a fraction of the cost as compared to other sequencing-based methods. Therefore, the use of large- scale screening for AIHL risk in the cystic fibrosis community should be re-visited. This article is protected by copyright. All rights reserved.
Keyphrases
  • cystic fibrosis
  • pseudomonas aeruginosa
  • lung function
  • healthcare
  • mental health
  • single cell
  • high glucose
  • endothelial cells
  • chronic obstructive pulmonary disease
  • air pollution
  • acinetobacter baumannii