Chemical composition, Aedes mosquito larvicidal activity, and repellent activity against Triatoma rubrofasciata of Severinia monophylla leaf essential oil.
Prabodh SatyalHo Viet HieuNguyen Thi Hong ChuongNguyen Huy HungLe Hoang SinhPham Van TheThieu Anh TaiVu Thi HienWilliam N SetzerPublished in: Parasitology research (2019)
Aedes aegypti and Ae. albopictus are key vectors in the spread of arboviruses such as dengue, chikungunya, yellow fever, and Zika. Triatoma rubrofasciata is an "assassin bug" whose populations and association with humans have dramatically increased and may represent a serious health concern. Control of insect vectors is a logical course of action to prevent the spread of these insect-borne infections. This work presents the leaf essential oil composition, mosquito larvicidal activities, and insect-repellent activity of Severinia monophylla. The essential oil of S. monophylla from Vietnam was obtained by hydrodistillation and analyzed by gas chromatography and mass spectrometry. The major components were sabinene, β-caryophyllene, bicyclogermacrene, germacrene D, (E)-nerolidol, globulol, and linalool. The leaf essential oil showed remarkable larvicidal activity against Ae. aegypti with LC50 (48 h) of 7.1 μg/mL and Ae. albopictus with LC50 (48 h) of 36 μg/mL. The essential oil also showed repellent activity on T. rubrofasciata at a concentration of 0.5%.
Keyphrases
- aedes aegypti
- essential oil
- zika virus
- dengue virus
- mass spectrometry
- gas chromatography
- healthcare
- liquid chromatography
- public health
- tandem mass spectrometry
- climate change
- high resolution mass spectrometry
- solid phase extraction
- risk assessment
- human health
- capillary electrophoresis
- gene therapy
- genetic diversity