Circulating levels of 3-hydroxymyristate, a direct quantification of endotoxaemia in noninfected cirrhotic patients.

Delphine WeilJean-Paul Pais de BarrosGuillaume MoureyCaroline LaheurteBenoit CyprianiNicolas BadetEric DelabrousseEmilie GrandclémentVincent Di MartinoPhilippe SaasLaurent LagrostThierry Thevenot

Published in: Liver international : official journal of the International Association for the Study of the Liver (2018)

In noninfected cirrhotic patients, 3-HM arises more frequently with impairment of liver function, heavy alcohol consumption, diabetic status, nonuse of beta blockers and a trend towards poorer outcome is also observed. The direct mass measurement of LPS using 3-HM appears reliable to detect transient endotoxaemia and promising to manage the follow-up of cirrhotic patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes
patient reported
wound healing