Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin-induced cardiotoxicity.
Can HuXin ZhangNing ZhangWen-Ying WeiLing-Li LiZhen-Guo MaQi-Zhu TangPublished in: Clinical and translational medicine (2020)
OSTN protects against DOX-elicited inflammation, oxidative stress, apoptosis, and cardiac dysfunction via activating PKG, and cardiac gene therapy with OSTN provides a novel therapeutic strategy against DOX-induced cardiotoxicity.