High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture.
Jérôme RobertEmily B ButtonSophie StukasGuilaine K BoyceEbrima GibbsCatherine M CowanMegan GilmourWai Hang ChengSonja K SooBrian YuenArvin BahrabadiKevin KangIva KulicGordon FrancisNeil CashmanCheryl L WellingtonPublished in: Molecular neurodegeneration (2017)
Our results define a novel activity of HDL that suppresses Aβ-mediated monocyte adhesion to the cerebrovascular endothelium.