CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.

Ștefan-Cristian VesaSonia Irina VlaicuVitalie VacarasSorin CrisanOctavia SabinSergiu PascaAdrian Pavel TrifaTamas Rusz-FogarasiMadalina SavaAnca Dana Buzoianu

Published in: Genes (2020)

We documented that CYP4F2 and VKORC1 polymorphisms boost the proinflammatory plaque environment (observed indirectly through the presence of ischemic heart disease), increasing the risk of plaque development.

Keyphrases

coronary artery disease