Collagen density regulates the activity of tumor-infiltrating T cells.
Dorota E KuczekAnne Mette H LarsenMarie-Louise ThorsethMarco CarrettaAdrija KalvisaMajken S SiersbækAna Micaela C SimõesAnne RoslindLars H EngelholmElfriede NoessnerMarco DoniaInge Marie SvanePer Thor StratenLars GrøntvedDaniel Hargbøl MadsenPublished in: Journal for immunotherapy of cancer (2019)
Our study identifies a new immune modulatory mechanism, which could be essential for suppression of T cell activity in the tumor microenvironment.
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