Intravoxel incoherent motion diffusion-weighted imaging for assessment of histologic grade of hepatocellular carcinoma: comparison of three methods for positioning region of interest.
Yi WeiFeifei GaoMin WangZixing HuangHehan TangJiaxing LiYi WangTong ZhangXiaocheng WeiDandan ZhengXijiao LiuPublished in: European radiology (2018)
• Diffusion MRI is useful for non-invasively differentiating the histologic grade of hepatocellular carcinoma. • Different ROI positioning methods used significantly affect the IVIM parameters and ADC measurements. • IVIM model is advantageous over mono-exponential model for assessing the histologic grade of hepatocellular carcinoma.