Parents of ataxia-telangiectasia patients display a distinct cellular immune phenotype mimicking ATM-mutated patients.

İsmail ÖğülürTugce ErtuzunBurcu KocamisYasemin Kendir DemirkolEmel UyarAyça KiykimDilek BaserGozde YesilHacer AkturkAyper SomerAhmet Ozen Elif Karakoç AydınerMeltem MuftuogluSafa Barış

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)

Parents of AT patients could present with recurrent infections and display cellular defects that mimic AT patients. The observed immunological changes could be associated with increased DNA double-strand breaks.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
oxidative stress
single molecule