Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy.

Yi Chieh LimKamilla E JensenDiana Aguilar-MoranteLina VardouliKristoffer Vitting-SeerupRyan C GimpleQiulian WuHenriette PedersenKirstine J ElbaekIrina GromovaRobert IhnatkoBjarne W KristensenJeanette K PetersenJane Skjoth-RasmussenWilliam FlavahanJeremy N RichPetra Hamerlik

Published in: Neuro-oncology (2022)

PFKM drives novel molecular pathways in GBM, offering a translational path to a novel therapeutic paradigm.

Keyphrases

cell migration
genome wide
metastatic colorectal cancer
gene expression
mesenchymal stem cells
cell therapy