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Botulinum Toxin-A for the Treatment of Myogenous Temporomandibular Disorders: An Umbrella Review of Systematic Reviews.

Giancarlo De la Torre CanalesMariana Barbosa Câmara-SouzaMalin ErnbergEssam Ahmed Al-MoraissiAnastasios GrigoriadisRodrigo Lorenzi PoluhaMaria ChristidisHajer JasimAnna LövgrenNikolaos Christidis
Published in: Drugs (2024)
The synthesis in this umbrella review provides the highest level of evidence present. Taken together, there are indications of effectiveness of BoNT-A for treatment of M-TMDs, supported by moderate evidence. However, considering the risk of causing serious adverse events, treatment with BoNT-A is recommended to be the last treatment alternative.
Keyphrases
  • systematic review
  • botulinum toxin
  • combination therapy
  • smoking cessation