Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study.
Gijsbert M KalisvaartRichard E EvenhuisWillem GrootjansThomas Van Den BergheMartijn CallensJudith V M G BovéeDavid CreytensAndré B P van KuilenburgFrank M SpeetjensLore LapeireGwen M L SysMarta FioccoKoenraad L VerstraeteMichiel Adreanus van de SandeJohan L BloemPublished in: Cancers (2024)
The predicted poor chemo response with MRI (rWIR < 2.3) is associated with shorter EFS even when adjusted for known clinical covariates and shows similar results to histological response evaluation. rWIR is a potential tool for future response-based individualized healthcare in osteosarcoma patients before surgical resection.
Keyphrases
- magnetic resonance imaging
- healthcare
- free survival
- end stage renal disease
- ejection fraction
- contrast enhanced
- newly diagnosed
- chronic kidney disease
- computed tomography
- prognostic factors
- photodynamic therapy
- squamous cell carcinoma
- magnetic resonance
- radiation therapy
- social media
- drug delivery
- climate change
- locally advanced
- patient reported
- patient reported outcomes
- health insurance