Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase-Signal Transducers and Activators of Transcription Signaling.

Matthew T PatrickRajan P NairKevin HePhilip E StuartAllison C BilliXiang ZhouJohann E GudjonssonJorge R OksenbergJames T ElderLam C Tsoi

Published in: Annals of neurology (2023)

By investigating the shared genetics of psoriasis and MS, along with their modifiable risk factors, our findings will advance innovations in treatment for patients suffering from comorbidities. ANN NEUROL 2023.

Keyphrases

multiple sclerosis
risk factors
end stage renal disease
ejection fraction
chronic kidney disease
mass spectrometry
ms ms
peritoneal dialysis
prognostic factors
transcription factor
tyrosine kinase
patient reported outcomes
gene expression
white matter
smoking cessation
replacement therapy