Impact of Metformin Use on Survival in Patients Undergoing Liver Resection for Colorectal Cancer Metastases.
Christof KaltenmeierBrittany MoroccoHamza YazdaniKatherine Moll ReitzKelley MeyerMichele MolinariDavid GellerSamer TohmePublished in: The American surgeon (2021)
In this study, we found that patients with CRLM on metformin have prolonged RFS and OS postliver resection. Further prospective randomized trials need to be carried out to evaluate the anti-neoplastic effect of metformin in diabetic and non-diabetic cancer patients.