Dentistry has changed significantly in the last two decades. Interdisciplinary treatment planning strives to deliver the highest quality of care through innovative collaborations among providers and the patient. The complexity of the care and challenges in interdisciplinary team communications are primary hurdles. We discuss five principles of interdisciplinary orthodontic-restorative treatment and outline a four-step interdisciplinary treatment planning process, starting with a comprehensive clinical examination to collect subjective and objective data. Diagnostic records, including 3D models, videos, 2D photos, questionnaires, and reports, are then evaluated to develop a problem list and treatment objectives. Treatment simulation is used to envision the outcome and guide the formulation of an orthodontic-restorative treatment plan. The plan can be broken down into stages, depending on the condition of the teeth and the planned restorative treatment. The challenges and opportunities presented by digital dentistry and the potential for more efficient interdisciplinary treatment are presented. In sum, this article provides an overview of the principles and framework for interdisciplinary orthodontic-restorative treatment, emphasising the importance of collaboration, communication and comprehensive treatment planning.