Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis.
Reem AssiChahrazad CherifiFrederique M F CornelisQiongfei ZhouLies StormsSofia PazminoRodrigo Coutinho de AlmeidaIngrid MeulenbeltRik Ju LoriesSilvia MonteagudoPublished in: Annals of the rheumatic diseases (2023)
Targeting KDM7A/B histone demethylases could be an attractive strategy to protect joints against osteoarthritis.