Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration.

Ranganayaki MuralidharanAnish BabuNarsireddy AmreddyKanthesh BasalingappaMeghna MehtaAllshine ChenYan Daniel ZhaoUday B KompellaAnupama MunshiRajagopal Ramesh

Published in: Journal of nanobiotechnology (2016)

Our results demonstrate that HuR is a molecular target for lung cancer therapy and its suppression using HuR-FNP produced significant therapeutic efficacy in vitro.

Keyphrases

cancer therapy
binding protein
drug delivery
signaling pathway
single molecule