Genetic Polymorphisms of MMP1, MMP9, COL1A1, and COL1A2 in Polish Patients with Thoracic Aortopathy.

Iwona Gorący Seweryn Grudniewicz Krzysztof Safranow Andrzej Ciechanowicz Paweł Jakubiszyn Anna Gorący Mirosław Brykczyński

Published in: Disease markers (2020)

The results of our study did not support associations between MMP1, MMP9, COL1A1, and COL1A2 genetic variants with the risk of thoracic artery disease in Polish patients. However, rs1799750 MMP1 and rs3918242 MMP9 seem to be associated with the degree of aortic regurgitation.

Keyphrases

cell migration
aortic valve
spinal cord
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
heart failure
coronary artery disease
coronary artery
pulmonary hypertension
spinal cord injury
patient reported
aortic dissection