Validated outcome of treatment changes according to International League Against Epilepsy criteria in adults with drug-resistant focal epilepsy.

Marco MulaGaetano ZaccaraCarlo Andrea GalimbertiBruno FerròMaria Paola CaneviniAddolorata MasciaOriano MecarelliRoberto MichelucciLaura Rosa PisaniLuigi Maria SpecchioSalvatore StrianoEmilio Perucca

Published in: Epilepsia (2019)

This study validates the use of ILAE treatment outcome criteria in a real-life setting, providing validated estimates of seizure freedom in patients with drug-resistant focal epilepsy in relation to the number of previously failed AEDs. Fewer than one in 10 patients achieved seizure freedom on a newly introduced AED over the study period. Pseudo drug resistance could be identified in one of five cases.

Keyphrases

drug resistant
multidrug resistant
acinetobacter baumannii
end stage renal disease
temporal lobe epilepsy
chronic kidney disease
ejection fraction
newly diagnosed
peritoneal dialysis
cystic fibrosis