Plasmid mediated colistin resistant mcr-1 and co-existence of OXA-48 among Escherichia coli from clinical and poultry isolates: first report from Nepal.
Bijaya MuktanUpendra Thapa ShresthaBinod DhungelBagish Chandra MishraNabaraj ShresthaNabaraj AdhikariMegha Raj BanjaraBipin AdhikariKomal Raj RijalPrakash GhimirePublished in: Gut pathogens (2020)
The high prevalence of colistin and carbapenem resistant genes, and their co-existence in plasmid DNA of E. coli isolates in this study suggests the possible spread to other animal, human and environmental pathogens. Molecular methods in addition to the conventional diagnostics in laboratories can help in early diagnosis, effective management and control of their potential transmission.
Keyphrases
- escherichia coli
- klebsiella pneumoniae
- endothelial cells
- acinetobacter baumannii
- biofilm formation
- single molecule
- genetic diversity
- gram negative
- human health
- circulating tumor
- antimicrobial resistance
- multidrug resistant
- pseudomonas aeruginosa
- induced pluripotent stem cells
- staphylococcus aureus
- gene expression
- risk assessment
- drug resistant
- tertiary care
- crispr cas
- circulating tumor cells