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Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19.

Felice D'AgnilloKathie-Anne WaltersYongli XiaoZong-Mei ShengKelsey ScherlerJaekeun ParkSebastian GygliLuz Angela RosasKaitlyn SadtlerHeather KalishCharles A BlattiRuoqing ZhuLisa P GatzkeColleen B BushellMatthew J MemoliSteven J O'DayTrevan D FischerTerese C HammondRaymond C LeeJ Christian CashMatthew E PowersGrant E O'KeefeKelly J ButnorAmy V RapkiewiczWilliam D TravisScott P LayneJohn C KashJeffery K Taubenberger
Published in: Science translational medicine (2021)
[Figure: see text].
Keyphrases
  • endothelial cells
  • coronavirus disease
  • sars cov
  • dna damage
  • oxidative stress
  • smoking cessation
  • stress induced