In Situ-Forming Collagen/poly-γ-glutamic Acid Hydrogel System with Mesenchymal Stem Cells and Bone Morphogenetic Protein-2 for Bone Tissue Regeneration in a Mouse Calvarial Bone Defect Model.

Sun-Hee ChoKeun Koo ShinSun-Young KimMi Young ChoDoo-Byoung OhYong Taik Lim

Published in: Tissue engineering and regenerative medicine (2022)

The Col/γ-PGA(mBMSC/BMP-2) hydrogel was suggested to be a promising platform by combining collagen as a major component of the extracellular matrix and γ-PGA as a viscosity reducer for easy handling at room temperature in BMSC-based bone tissue engineering scaffolds.

Keyphrases

tissue engineering
bone regeneration
room temperature
extracellular matrix
mesenchymal stem cells
bone mineral density
soft tissue
wound healing
stem cells
bone loss
umbilical cord
postmenopausal women
ionic liquid
bone marrow
high throughput
body composition