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Comparison of Structural Changes in Nodding Syndrome and Other Epilepsies Associated With Onchocerca volvulus .

Rajarshi MazumderSamson Kamya LubowaNoriko SalamonPhD Nicholas J JacksonMichael KawooyaPamela Rosemary AkunRonald AnguzuRodney J OgwangJoseph KubofcikThomas B NutmanKevin MarshCharles NewtonAngela VincentRichard Idro
Published in: Neurology(R) neuroimmunology & neuroinflammation (2022)
This is the first study to show that cerebral and cerebellar atrophy correlated with the severity of NS disability, providing an imaging marker for these endemic epileptic disorders that until now have remained poorly characterized. Both NS and OAE have cerebral and cerebellar atrophy, and the levels of Ov-associated antibodies do not seem to be related to the structural changes on MRI.
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