HOMER3 facilitates growth factor-mediated β-Catenin tyrosine phosphorylation and activation to promote metastasis in triple negative breast cancer.
Qinghua LiuLixin HeSiqi LiFengyan LiGuangzheng DengXinjian HuangMuwen YangYunyun XiaoXiangfu ChenYing OuyangJinxin ChenXuxia WuXi WangLibing SongChuyong LinPublished in: Journal of hematology & oncology (2021)
These findings identify a novel role of HOMER3 in the transduction of growth factor-mediated β-Catenin activation and suggest that HOMER3 might be a targetable vulnerability of TNBC.