A Clinical Cassette Dosing Study for Evaluating the Contribution of Hepatic OATPs and CYP3A to Drug-Drug Interactions.

Takashi YoshikadoKazuya MaedaSawako FurihataHanano TerashimaTakeshi NakayamaKeiko IshigameKazunobu TsunemotoHiroyuki KusuharaKen-Ichi FurihataYuichi Sugiyama

Published in: Pharmaceutical research (2017)

The DDI study clarified the rate-determining processes of OATP/CYP3A substrates. Our analyses provide valuable information for predicting complex drug-drug interactions involving multiple processes.

Keyphrases

emergency department